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Autoimmune Conditions

Rheumatic Fever

Rheumatic Fever on it's own may or may not be an autoimmune condition. RF is an inflammatory usually is caused by a poorly treated or untreated infection such as Strep, and so the antibodies begin attacking other areas, usually the heart, and can leave serious, permanent damage, including a narrowing of the heart valve (Valve stenosis), a leak in the valve that allows the blood to flow the wrong direction (Valve regurgitation) or inflammation to the heart muscle. Some of the damage may be permanent.

Initial symptoms of Rheumatic Fever might include a fever, joint pain with swelling and redness, nose bleeds, and skin rashes.

Rheumatic Fever is rare in the United States in recent years, but there is still an occasion where a case of Rheumatic Fever does occur. It typically occurs in children between the ages of 6-15, and usually within 20 days of strep throat or scarlet fever. The reason it is so rare in the U.S. and other developed countries is because the treatment of Strep and other infections are usually effective enough to take care of the infection, and not give Rheumatic Fever the chance to set in.

 

Symptoms:

Abdominal pain
Bleeding from the nose
Fever
General joint pain and stiffness
Nodules under the skin
Shortness of breath

 

Diagnosis:

To diagnose Rheumatic Fever, your physician begins with the typical exam and symptom history, as well as history of recent infections. They may also perform an electrocardiogram to check your heart. Blood tests may show:

Elevated Erythrocyte Sedimentation Rate
Elevated C-Reactive Protein
Elevated White Blood Cell Count
Elevated Leukocytes
Elevated Antistreptolysin O Titre

There is also certain criteria that must be met before a physician can confirm a Rheumatic Fever diagnosis, broken down into Major Criteria and Minor Criteria. (source: UW Health)

Major Criteria:

- Arthritis in several joints (polyarthritis)
- Heart inflammation (carditis)
- Nodules under the skin (subcutaneous skin nodules)
- Rapid, jerky movements (chorea, Sydenham chorea)
- Skin rash (erythema marginatum)

Minor Criteria:

- Fever
- High ESR
- Joint pain
- Other laboratory findings

Treatment:

The goal of treatment is to destroy the strep bacteria or other bacteria causing the Rheumatic Fever, while relieving the symptoms of inflammation. Preventative measures might also be taken in order to control relapses of the Rheumatic Fever.

The treatment may include antibiotics, and in severe cases the antibiotic will be continued even after the offending bacteria is gone to prevent a relapse. Non-steroidal anti-inflammatories might be used to reduce inflammation.

Prognosis:

Heart damage from the Rheumatic Fever may not show up for years, so it is very important that you follow up with your physician regularly. For at least the first 3-5 years, low-dose antibiotics will more than likely be taken for prevention. If low-dose antibiotics are not taken, Rheumatic Fever will relapse.

 

 
 
 

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