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Autoimmune Conditions

Bullous Pemphigoid (BP)

Bullous Pemphigoid (BP for short) is a rare autoimmune that causes fluid-filled blisters on the skin, usually on the arms, legs or trunk. It can also affect mucous membranes and the esophagus. BP is not a fatal disease, but the open sores can become infected and cause serious health issues and scars. Symptoms can range from mild to severe and may include itchy welts and blisters.

BP most commonly affects older adults and is rarely seen in children. BP is often associated with other autoimmune conditions such as Diabetes and Rheumatoid Arthritis.

Symptoms:

Blisters on the skin

Diagnosis:

Usually, diagnosis is made by visual exam, but may be confirmed through a skin biopsy. There are no blood tests that can conclusively diagnose BP.


Treatment:

There is no cure for BP , so treatment focuses on the relief of symptoms and prevention of infections. Medications might include Tetracycline and Minocycline.

More severe cases may require oral Corticosteroids such as Prednisone, and immunosuppressant therapy such as Azathioprine, Mycophenolate Mofetil, Methotrexate, Cyclophosphamide or other medications to tame the immune system.

Prognosis:

In most cases, BP eventually clears up on it's own, but flare ups are still possible even after long periods of remission.

 

 
 
 

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